In 1986, the scientific community learned that a gene involved in regulating cell growth had been discovered, HER2/NEU. About the same time Dr. Dennis Slamon and his team of researchers were extracting DNA from discarded breast cancer tissue looking for genetic alterations that might be linked to the disease. They learned that a mutation of the HER2/NEU gene resulted in an aggressive cancer in about 30% of the cases. The challenge was to find an antibody that would inhibit the growth of HER2/NEU. This is the decade-long story of the discovery of Herceptin, an antibody that blocks the signals for uncontrolled growth.

Health Collection

HER2/NEU gene, breast cancer tissue, mutations, cell growth, Herceptin, biological therapy, antibody, clinical trials, results of Herceptin trials, Cancer

Allied Health, School and Community Health, Personal Health, The Human Condition

Slamon, Dennis (Performer), INTELECOM Intelligent Telecommunications (Firm)

00:03:07 (HH:MM:SS)

English

Name	INTELECOM Intelligent Telecommunications
Role	Distributor
Telephone	800-576-2988 x122
Address	150 E. Colorado Blvd. Ste. 300, Pasadena, CA 91105
Email	[email protected]

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